Prostate cancer. It is now the second most common form of cancer for men in the United States, according to data from the CDC’s U.S. Cancer Statistics Working Group, with one in nine men being diagnosed with the disease.1 But what is perhaps even more concerning, is that that prostate cancer is no longer a disease exclusive to older men, as the number of young men diagnosed with the disease has increased six-fold in the last 20 years.2 The increasing rates of prostate cancer is driving the global market for Prostate Cancer Therapeutics , which is expected to reach $13.1 billion by 2022.3
It is likely that nutrient deficiencies from poor diet and less nutrient-rich foods are a factor in this trend. In fact, there is mounting research that nutritional solutions can support prostate health and even reduce incidence and mortality of prostate cancer. Selenium is a primary example. A particularly compelling study in the Journal of the American Medical Association found that 200µg per day of SelenoExcell®, high selenium yeast, supported a 63 percent reduction in prostate cancer and 50 percent overall reduction in cancer mortality.4 Additional analysis of the study suggested that the results were most pronounced in men with lower baseline blood selenium levels, a lower PSA and in younger men.5
The body of research is so significant that the FDA has even approved a qualified health claim for products that contain selenium regarding a reduction in the risk of certain cancers and selenium’s anti-carcinogenic effects in the body.6
Given that it is so difficult to achieve adequate nutrient level from diet alone—research has also shown that modern agriculture’s emphasis on crop size and yield has depleted our soils of key micronutrients like selenium, magnesium and zinc, and resulted in produce that is significantly lower in nutritional value than 50 years ago7—it makes increasing sense that nutritional supplementation with nutrients like selenium have an important role to play.
Use of selenium is especially intriguing for prostate health. But as supplement manufacturers look further at this opportunity, it is important to recognize that not all selenium ingredients are equally effective. Research looking a direct comparisons between SelenoExcell® high selenium yeast and selenomethionine (SeMet) found that the SelenoExcell® outperformed the SeMet in healthy men for both bioavailability and bioefficacy.8
Beyond clinical, efficacy, SelenoExcell® is an ingredient that is both easy to use and cost-effective in a variety of formulations. For such a powerhouse and clinically proven trace mineral SelenoExcell® is surprisingly affordable to add to products, with the clinically effective dose of 200µg per day adding a cost of $0.163 per dose. Made with whole food, fermented, food-grade yeast, SelenoExcell® is also the first selenium ingredient to have GRAS (Generally Recognized as Safe) status for use in food and beverage products.
To learn more about important opportunities to develop relevant products with selenium for prostate support and overall health, we have gathered a broad range of resources to cover a variety of business needs, from current clinical research to formulation insights and strategies.
Inside our Prostate Market Spotlight:
- Formulator's Corner, by Jim Roufs, MS, RD: Selenium and Optimal Prostate Health
- Research Review, by Mark Whitacre, PhD: Prostate Health
- Product Highlights: Best in Class Product from Doctor’s Best and Healthy Origins
- White Paper: Why Selenium-enriched yeast? Personalized medicine’s most useful mineral